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In///ce//st causes increased risk of infertility, miscarriage, cleft palates, heart conditions, facial asymmetry, low birth weight, slow growth rate and neonatal mortality. "Even if there's not always a mutation, in///breeding brings up a lot of problems involving recessive traits.
In///breeding increases the homozygosity which in turn results into the expression of autosomal recessive genes that may be one of the causes for abnormal brain development and function.

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